Autorinnen und Autoren des Paul-Ehrlich-Instituts sind durch Fettdruck kenntlich gemacht. Wenn Online-Abstracts oder Volltexte zu den Publikationen verfügbar sind, so sind diese verlinkt.
Heinl PV, Graulich E, Weigmann B, Wangorsch A, Ose R, Bellinghausen I, Khatri R, Raker VK, Scheurer S, Vieths S, Saloga J, Steinbrink K (2024): IL-10-modulated dendritic cells from birch pollen- and hazelnut-allergic patients facilitate Treg-mediated allergen-specific and cross-reactive tolerance.
Allergy Jul 28 [Epub ahead of print].
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Lin YJ, Zimmermann J, Schülke S (2024): Novel adjuvants in allergen-specific immunotherapy: where do we stand?.
Front Immunol Feb 23 [Epub ahead of print].
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Steigerwald H, Blanco-Peréz F, Macías-Camero A, Albrecht M, Huch M, Bender C, Schülke S, Keller J, Krause M, Barbas C, Gonzalez-Menendez I, Quintanilla-Martinez L, Toda M, Barber D, Kulling S, Bunzel M, Vieths S, Villasenor A, Stoll D, Scheurer S (2024): Effects of pectin methyl-esterification on intestinal microbiota and its immunomodulatory properties in naive mice.
Carbohydrate Polymers 334: 122007.
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Wangorsch A, Jamin A, Spiric J, Vieths S, Scheurer S, Mahler V, Hofmann SC (2024): Allergic Reaction to a Commercially Available Insect Snack Caused by House Cricket (Acheta domesticus) Tropomyosin.
Mol Nutr Food Res 68: 2300420.
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He C, Liu Y, Schülke S, Nishio S, Guo Y, Rainer H, Krause M, Cheng TJ, Nochi T, Vieths S, Scheurer S, Matsuda T, Toda M (2023): β-1,3-glucan, but not β-1,3/1,6-glucan, exacerbates experimental food allergy, while both increase IgA induction.
Allergy 79: 503-506.
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Lin YJ, Jamin A, Wolfheimer S, Fiedler A, Junker AC, Goretzki A, Scheurer S, Schülke S (2023): A flagellin-conjugate protein induces dual NLRC4- and NLRP3-inflammasome activation which modulates inflammatory cytokine secretion from macrophages.
Front Immunol 14: 1136669.
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Scheurer S, Junker AC, He C, Schülke S, Toda M (2023): The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses.
Curr Allergy Asthma Rep 23: 589-600.
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Steigerwald H, Krause M, Gonzalez-Menendez I, Quintanilla-Martinez L, Vieths S, Scheurer S, Albrecht M, Blanco-Pérez F (2023): Peach extract induces systemic and local immune responses in an experimental food allergy model.
Sci Rep 13: 1892.
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Blanco-Pérez F, Gonzalez-Menendez I, Stassen M, Kato Y, Laiño J, Kirberg J, Krause M, Martella M, Shibata N, Quintanilla-Martinez L, Feyerabend TB, Rodewald HR, Galli SJ, Vieths S, Scheurer S, Toda M (2022): Mast cells partly contribute to allergic enteritis development: findings in two different mast cell-deficient mice.
Allergy 77: 1051-1054.
Online-Abstract
Goretzki A, Lin YJ, Zimmermann J, Rainer H, Junker AC, Wolfheimer S, Vieths S, Scheurer S, Schülke S (2022): Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein.
Int J Mol Sci 23: 12695.
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Steigerwald H, Blanco-Perez F, Albrecht M, Bender C, Wangorsch A, Endreß HU, Bunzel M, Mayorga C, Torres MJ, Scheurer S, Vieths S (2022): Does the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins?.
Foods 11: 13.
Online-Abstract
Wangorsch A, Lidholm J, Mattsson LA, Larsson H, Reuter A, Gubesch M, Gadermaier G, Bures P, Scheurer S, Ballmer-Weber B, Vieths S (2022): Identification of a defensin as novel allergen in celery root: Api g 7 as a missing link in the diagnosis of celery allergy?.
Allergy 77: 1294-1296.
Online-Abstract
Wangorsch A, Scheurer S, Blanca M, Blanca-Lopez N, Somoza ML, Martin-Pedraza L (2022): Allergenic Properties and Molecular Characteristics of PR-1 Proteins.
Front Allergy 3: 824717.
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Zimmermann J, Goretzki A, Meier C, Wolfheimer S, Lin YJ, Rainer H, Krause M, Wedel S, Spies G, Führer F, Vieths S, Scheurer S, Schülke S (2022): Modulation of dendritic cell metabolism by an MPLA-adjuvanted allergen product for specific immunotherapy.
Front Immunol 13: 916491.
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Blanco-Pérez F, Steigerwald H, Schülke S, Vieths S, Toda M, Scheurer S (2021): The Dietary Fiber Pectin: Health Benefits and Potential for the Treatment of Allergies by Modulation of Gut Microbiota.
Curr Allergy Asthma Rep 21: 43.
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Cheng TY, Lin YJ, Saburi W, Vieths S, Scheurer S, Schülke S, Toda M (2021): β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.
Cells 10: 1774.
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De Marchi L, Mainente F, Leonardi M, Scheurer S, Wangorsch A, Mahler V, Pilolli R, Sorio D, Zoccatelli G (2021): Allergenicity assessment of the edible cricket Acheta domesticus in terms of thermal and gastrointestinal processing and IgE cross-reactivity with shrimp.
Food Chem 359: 129878.
Online-Abstract
Gonzalez-Klein Z, Cuevas-Zuviria B, Hernandez-Ramirez G, Wangorsch A, Pazos-Castro D, Romero-Sahagun A, Pacios LF, Tome-Amat J, Scheurer S, Diaz-Perales A, Garrido-Arandia M (2021): The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization.
Biochim Biophys Acta Mol Cell Biol Lipids 1866: 158928.
Online-Abstract
Krause M, Crauwels P, Blanco Pérez F, Globisch M, Wangorsch A, Henle T, Lidholm J, van Zandbergen G, Vieths S, Scheurer S, Toda M (2021): Human monocyte-derived type 1 and 2 macrophages recognize Ara h 1, a major peanut allergen, by different mechanisms.
Sci Rep 11: 10141.
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Lin YJ, Flaczyk A, Wolfheimer S, Goretzki A, Jamin A, Wangorsch A, Vieths S, Scheurer S, Schülke S (2021): The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells.
Cells 10: 3415.
Online-Abstract
Lin YJ, Papp G, Miskey C, Fiedler A, Goretzki S, Wolfheimer S, Crauwels P, Ivics Z, van Zandbergen G, Vieths S, Scheurer S, Schülke S (2021): The flagellin:allergen fusion protein rFlaA:Betv1 induces a MyD88- and MAPK-dependent activation of glucose metabolism in macrophages.
Cells 10: 2614.
Online-Abstract
Scheurer S, van Ree R, Vieths S (2021): The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area.
Curr Allergy Asthma Rep 21: 7.
Online-Abstract
Wangorsch A, Jamin A, Eichhorn S, Pablos I, Sharma S, Schweidler B, Kastner B, Wildner S, Saloga J, Führer F, Reyna Orozco RR, Sherkat R, Sadeghi S, Teifoori F, Park JW, Briza P, Vieths S, Ferreira F, Arora N, Lidholm J, Gadermaier G, Scheurer S (2021): Component-Resolved Diagnosis of American Cockroach (Periplaneta americana) Allergy in Patients From Different Geographical Areas.
Front Allergy 2: 691627.
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Martín-Pedraza L, Wangorsch A, Bueno-Diaz C, De Las Heras M, Scheurer S, Cuesta-Herranz J, Villalba M (2020): 2S Albumins and nsLTP Are Involved in Anaphylaxis to Pizza Sauce: IgE Recognition Before and After Allergen Processing.
Food Chem 321: 126679.
Online-Abstract
Wangorsch A, Kulkarni A, Jamin A, Spiric J, Bräcker J, Brockmeyer J, Mahler V, Blanca-López N, Ferrer M, Blanca M, Torres M, Gomez P, Bartra J, García-Moral A, Goikoetxea MJ, Vieths S, Toda M, Zoccatelli G, Scheurer S (2020): Identification and Characterization of IgE-reactive Proteins and a New Allergen (Cic a 1.01) from Chickpea (Cicer arietinum).
Mol Nutr Food Res 64: e2000560.
Online-Abstract
Blanco-Pérez F, Kato Y, Gonzalez-Menendez I, Laiño J, Ohbayashi M, Burggraf M, Krause M, Kirberg J, Iwakura Y, Martella M, Quintanilla-Martinez L, Shibata N, Vieths S, Scheurer S, Toda M (2019): CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis.
Sci Rep 9: 9608.
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Moeller T, Wolfheimer S, Goretzki A, Scheurer S, Schülke S (2019): NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein.
Cells 8: 355.
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Safi H, Wangorsch A, Lidholm J, Brini F, Spiric J, Rihs HP, Vieths S, Armentia A, Farioli L, Diaz-Perales A, Pastorello EA, Scheurer S (2019): Identification and molecular characterization of allergenic nsLTP from durum wheat (Triticum turgidum).
Clin Exp Allergy 49: 120-129.
Online-Abstract
Anzaghe M, Schülke S, Scheurer S (2018): Virus-Linke Particles as Carrier Systems to Enhance Immunomodulation in Allergen Immunotherapy.
Curr Allergy Asthma Rep 18: 71.
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Gogesch P, Schülke S, Scheurer S, Mühlebach MD, Waibler Z (2018): Modular MLV-VLPs co-displaying ovalbumin peptides and GM-CSF effectively induce expansion of CD11b+ APC and antigen-specific T cell responses in vitro.
Mol Immunol 101: 19-28.
Online-Abstract
Scheurer S, Schülke S (2018): Interaction of Non-Specific Lipid-Transfer Proteins With Plant-Derived Lipids and Its Impact on Allergic Sensitization.
Front Immunol 9: 1389.
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Schülke S, Fiedler AH, Junker C, Flaczyk A, Wolfheimer S, Heinz A, Beckert H, Nagl B, Bohle B, Vieths S, Toda M, Scheurer S (2018): Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization.
J Allergy Clin Immunol 141: 1786-1798.
Online-Abstract
Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S (2018): Author Correction: Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo.
Sci Rep 8: 2745.
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Akhras S, Toda M, Boller K, Himmelsbach K, Elgner F, Biehl M, Scheurer S, Gratz M, Vieths S, Hildt E (2017): Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8+ T-cell response.
Sci Rep 7: 9630.
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Laiño J, Wangorsch A, Blanco F, Wolfheimer S, Krause M, Flaczyk A, Möller TM, Tsai M, Galli S, Vieths S, Toda M, Scheurer S, Schülke S (2017): Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice.
J Immunol Res 2017: 7983217.
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Scheurer S, Toda M (2017): Epicutaneous immunotherapy.
Allergol Immunopathol (Madr) Nov 3 [Epub ahead of print].
Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S (2017): Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo.
Sci Rep 7: 11782.
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Wangorsch A, Jamin A, Lidholm J, Gräni N, Lang C, Ballmer-Weber B, Vieths S, Scheurer S (2017): Identification and implication of an allergenic PR-10 protein from walnut in birch pollen associated walnut allergy.
Mol Nutr Food Res 61: 1600902.
Online-Abstract
Husslik F, Nürnberg J, Seutter von Loetzen C, Mews T, Ballmer-Weber BK, Kleine-Tebbe J, Treudler R, Simon JC, Randow S, Völker E, Reuter A, Rösch P, Vieths S, Holzhauser T, Schiller D (2016): The conformational IgE epitope profile of soybean allergen Gly m 4.
Clin Exp Allergy 46: 1484-1497.
Online-Abstract
Schülke S, Scheurer S (2016): Immunologische Grundlagen und Pathomechanismen von Lebensmittelallergien.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 59: 723-731.
Online-Abstract
Schülke S, Vogel L, Junker AC, Hanschmann KM, Flaczyk A, Vieths S, Scheurer S (2016): A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro.
J Immunol Res 2016: 1-8.
Online-Abstract
Wangorsch A, Larsson H, Messmer M, García-Moral A, Lauer I, Wolfheimer S, Schülke S, Bartra J, Vieths S, Lidholm J, Scheurer S (2016): Molecular cloning of plane pollen allergen Pla a 3 and its utility as diagnostic marker for plane pollen associated peach allergy.
Clin Exp Allergy 46: 764-774.
Online-Abstract
Lorenz AR, Scheurer S, Vieths S (2015): Food allergens: molecular and immunological aspects, allergen databases and cross-reactivity.
Chem Immunol Allergy 101: 18-29.
Online-Abstract
Petersen A, Kleine-Tebbe J, Scheurer S: Stabile pflanzliche Nahrungsmittelallergene I: Lipid-Transfer-Proteine.
In: Kleine-Tebbe J, Jakob T (Hrsg.), Molekulare Allergiediagnostik. Berlin [u.a.]: Springer-Verlag, 2015. S. 45-59, ISBN 978-3-662-45220-2
Scheurer S, Toda M, Vieths S (2015): What makes an allergen?.
Clin Exp Allergy 45: 1150-1161.
Online-Abstract
Schülke S, Flaczyk A, Vogel L, Gaudenzio N, Angers I, Löschner B, Wolfheimer S, Spreitzer I, Qureshi S, Tsai M, Galli S, Vieths S, Scheurer S (2015): MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison to LPS.
Allergy 70: 1259-1268.
Online-Abstract
Siebeneicher S, Reuter S, Wangorsch A, Krause M, Foetisch K, Heinz A, Naito S, Reuter A, Taube C, Vieths S, Scheurer S, Toda M (2015): Epicutaneous immunotherapy with a hypoallergenic Bet v 1 suppresses allergic asthma in a murine model.
Allergy 70: 1559-1568.
Online-Abstract
Uhlig KM, Schülke S, Scheuplein VA, Malczyk AH, Reusch J, Kugelmann S, Muth A, Koch V, Hutzler S, Bodmer BS, Schambach A, Buchholz CJ, Waibler Z, Scheurer S, Mühlebach MD (2015): Lentiviral protein transfer vectors are an efficient vaccine-platform inducing strong antigen-specific cytotoxic T cell response.
J Virol 89: 9044-9060.
Online-Abstract
Wangorsch A, Jamin A, Foetisch K, Malczyk A, Reuter A, Vierecke S, Schülke S, Bartel D, Mahler V, Lidholm J, Vieths S, Scheurer S (2015): Identification of Sola l 4 as Bet v 1 homologous pathogenesis related-10 allergen in tomato fruits.
Mol Nutr Food Res 59: 582-592.
Online-Abstract
Bolla M, Zenoni S, Scheurer S, Vieths S, San Miguel Moncin MD, Olivieri M, Antico A, Ferrer M, Berroa F, Enrique E, Avesani L, Marsano F, Zoccatelli G (2014): Pomegranate (Punica granatum L.) expresses several nsLTPs isoforms characterized by different Immunoblobulin E-binding properties.
Int Arch Allergy Immunol 164: 112-121.
Online-Abstract
Heilmann M, Wellner A, Gadermaier G, Ilchmann A, Briza P, Krause M, Nagai R, Burgdorf S, Scheurer S, Vieths S, Henle T, Toda M (2014): Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity.
J Biol Chem 289: 7919-7928.
Online-Abstract
Schülke S, Wolfheimer S, Gadermaier G, Wangorsch A, Siebeneicher S, Briza P, Spreitzer I, Schiller D, Loeschner B, Uematsu S, Ryffel B, Akira S, Waibler Z, Vieths S, Toda M, Scheurer S (2014): Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC.
PLoS One 9: e87822.
Online-Abstract
Siebeneicher S, Reuter S, Krause M, Wangorsch A, Maxeiner J, Wolfheimer S, Schülke S, Naito S, Heinz A, Taube C, Vieths S, Scheurer S, Toda M (2014): Epicutaneous immune modulation with Bet v 1 plus R848 suppresses allergic asthma in a murine model.
Allergy 69: 328-337.
Online-Abstract
Bohnen C, Wangorsch A, Schülke S, Nakajima-Adachi H, Hachimura S, Burggraf M, Süzer Y, Schwantes A, Sutter G, Waibler Z, Reese G, Toda M, Scheurer S, Vieths S (2013): Vaccination with recombinant modified vaccinia virus Ankara prevents the onset of intestinal allergy in mice.
Allergy 68: 1021-1028.
Online-Abstract
Fiocchi A, Annunziato F, Assa'ad A, Arshad H, Bahna SL, Boyle R, Brozek J, Bush A, Canonica W, Cicardi M, Compalati E, Dahdah L, Dupont C, Finegold I, Fineman SM, Grabenhenrich L, Holgate S, Kuitunen M, Lau S, Maggi E, Martelli A, Matricardi P, Moretta L, Palmer D, Parronchi P, Pawankar R, Prescott S, Restani P, Rosenwasser L, Terracciano L, Scheurer S, Tripodi S, Vieths S, von Berg A, Vultaggio A, Weber RW (2013): The management of paediatric allergy: not everybody's cup of tea--10-11th February 2012.
Curr Opin Allergy Clin Immunol 13: S1-S50.
Foetisch K, Scheurer S, Vieths S, Hanschmann KM, Lidholm J, Mahler V (2013): Identification of allergen-resolved threshold doses of carrot (Daucus carota) by means of oral challenge and ELISA.
J Allergy Clin Immunol 131: 1711-1713.
Hofmann C, Scheurer S, Rost K, Graulich E, Jamin A, Foetisch K, Saloga J, Vieths S, Steinbrink K, Adler HS (2013): Cor a 1-reactive T cells and IgE are predominantly cross-reactive to Bet v 1 in patients with birch pollen-associated food allergy to hazelnut.
J Allergy Clin Immunol 131: 1384-1392.
Online-Abstract
Micheal S, Wangorsch A, Wolfheimer S, Foetisch K, Minhas K, Scheurer S, Ahmed A (2013): Immunoglobulin E reactivity and allergenic potency of Morus papyrifera (paper mulberry) pollen.
J Investig Allergol Clin Immunol 23: 168-175.
Online-Abstract
Javaloyes G, Goikoetxea MJ, García Nuñez I, Aranda A, Sanz ML, Blanca M, Diaz Perales A, da Souza J, Esparza I, Del Pozo V, Blazquez AB, Scheurer S, Vieths S, Ferrer M (2012): Pru p 3 acts as a strong sensitizer for peanut allergy in Spain.
J Allergy Clin Immunol 130: 1432-1434.e3.
Javaloyes G, Goikoetxea MJ, García Nuñez I, Sanz ML, Blanca M, Scheurer S, Vieths S, Ferrer M (2012): Performance of different in vitro techniques in the molecular diagnosis of peanut allergy.
J Investig Allergol Clin Immunol 22: 508-513.
Online-Abstract
Trcka J, Schäd GG, Scheurer S, Conti A, Vieths S, Gross G, Trautmann A (2012): Rice-Induced Anaphylaxis: IgE-Mediated Allergy against a 56-kDa Glycoprotein.
Int Arch Allergy Immunol 158: 9-17.
Online-Abstract
Wangorsch A, Weigand D, Peters S, Mahler V, Fötisch K, Reuter A, Imani J, DeWitt AM, Kogel KH, Lidholm J, Vieths S, Scheurer S (2012): Identification of a Dau c PRPlike protein (Dau c 1.03) as a new allergenic isoform in carrots (cultivar Rodelika).
Clin Exp Allergy 42: 156-166.
Online-Abstract
Peters S, Imani J, Mahler V, Foetisch K, Kaul S, Paulus KE, Scheurer S, Vieths S, Kogel KH (2011): Dau c 1.01 and Dau c 1.02-silenced transgenic carrot plants show reduced allergenicity to patients with carrot allergy.
Transgenic Res 20: 547-556.
Online-Abstract
Petersen A, Scheurer S (2011): Stabile pflanzliche Nahrungsmittelallergene: Lipid-Transfer-Proteine.
Allergo J 20: 384-386.
Schülke S, Burggraf M, Waibler Z, Wangorsch A, Wolfheimer S, Kalinke U, Vieths S, Toda M, Scheurer S (2011): A fusion protein of flagellin and ovalbumin suppresses the TH2 response and prevents murine intestinal allergy.
J Allergy Clin Immunol 128: 1340-1348.
Online-Abstract
Schulten V, Lauer I, Scheurer S, Thalhammer T, Bohle B (2011): A food matrix reduces digestion and absorption of food allergens in vivo.
Mol Nutr Food Res 55: 1484-1491.
Online-Abstract
Schulten V, Nagl B, Scala E, Bernardi ML, Mari A, Ciardiello MA, Lauer I, Scheurer S, Briza P, Jürets A, Ferreira F, Jahn-Schmid B, Fischer GF, Bohle B (2011): Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut.
Allergy 66: 1005-1013.
Online-Abstract
Toda M, Reese G, Gadermaier G, Schulten V, Lauer I, Egger M, Briza P, Randow S, Wolfheimer S, Kigongo V, Del Mar San Miguel Moncin M, Fötisch K, Bohle B, Vieths S, Scheurer S (2011): Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen.
J Allergy Clin Immunol 128: 1022-1030.e7.
Online-Abstract
Hartz C, Lauer I, del Mar San Miguel-Moncín M, Cisteró-Bahíma A, Fötisch K, Lidholm J, Vieths S, Scheurer S (2010): Comparison of IgE-binding capacity, cross-reactivity and biological potency of allergenic non-specific lipid transfer proteins from peach, cherry and hazelnut.
Int Arch Allergy Immunol 153: 335-346.
Online-Abstract
Ilchmann A, Burgdorf S, Scheurer S, Waibler Z, Nagai R, Wellner A, Yamamoto Y, Yamamoto H, Henle T, Kurts C, Kalinke U, Vieths S, Toda M (2010): Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: Role of macrophage scavenger receptor class A type I and II.
J Allergy Clin Immunol 125: 175-183.e11.
Online-Abstract
Le LQ, Mahler V, Scheurer S, Foetisch K, Braun Y, Weigand D, Enrique E, Lidholm J, Paulus KE, Sonnewald S, Vieths S, Sonnewald U (2010): Yeast profilin complements profilin deficiency in transgenic tomato fruits and allows development of hypoallergenic tomato fruits.
FASEB J 24: 4939-4947.
Online-Abstract
Pokoj S, Lauer I, Fötisch K, Himly M, Mari A, Enrique E, Miguel-Moncin MS, Lidholm J, Vieths S, Scheurer S (2010): Pichia pastoris is superior to E. coli for the production of recombinant allergenic non-specific Lipid Transfer Proteins.
Protein Expr Purif 69: 68-75.
Online-Abstract
Schäd S, Trcka J, Lauer I, Scheurer S, Trautmann A (2010): Wine allergy in a wine-growing district: Tolerance Induction in a patient with allergy to grape lipid-transfer protein.
World Allergy Organiz J 3: 1-5.
Online-Abstract
Schülke S, Waibler Z, Mende S, Zoccatelli G, Vieths S, Toda M, Scheurer S (2010): Fusion protein of TLR5-ligand and allergen potentiates activation and IL-10 secretion in murine myeloid DC.
Mol Immunol 48: 341-350.
Online-Abstract
Zoccatelli G, Pokoj S, Foetisch K, Bartra J, Valero A, Del Mar San Miguel-Moncin M, Vieths S, Scheurer S (2010): Identification and characterization of the major allergen of green bean (Phaseolus vulgaris) as a non-specific lipid transfer protein (Pha v 3).
Mol Immunol 47: 1561-1568.
Online-Abstract
Cretich M, Di Carlo G, Giudici C, Pokoj S, Lauer I, Scheurer S, Chiari M (2009): Detection of allergen specific immunoglobulins by microarrays coupled to microfluidics.
Proteomics 9: 2098-2107.
Online-Abstract
Ilchmann A, Burgdorf S, Scheurer S, Waibler Z, Nagai R, Wellner A, Yamamoto Y, Yamamoto H, Henle T, Kurts C, Kalinke U, Vieths S, Toda M (2009): Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: role of macrophage scavenger receptor class A type I and II.
J Allergy Clin Immunol 125: 175-83.
Online-Abstract
Lauer I, Dueringer N, Pokoj S, Rehm S, Zoccatelli G, Reese G, Miguel-Moncin MS, Cistero-Bahima A, Enrique E, Lidholm J, Vieths S, Scheurer S (2009): The non-specific lipid transfer protein, Ara h 9, is an important allergen in peanut.
Clin Exp Allergy 39: 1427-1437.
Online-Abstract
Lorenz AR, Lüttkopf D, May S, Scheurer S, Vieths S (2009): The Principle of Homologous Groups in Regulatory Affairs of Allergen Products - A Proposal.
Int Arch Allergy Immunol 148: 1-17.
Online-Abstract
Scheurer S, Sonnewald S (2009): Genetic engineering of plant food with reduced allergenicity.
Front Biosci 14: 59-71.
Online-Abstract
Schulten V, Radakovics A, Hartz C, Mari A, Vazquez-Cortes S, Fernandez-Rivas M, Lauer I, Jahn-Schmid B, Eiwegger T, Scheurer S, Bohle B (2009): Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach.
J Allergy Clin Immunol 124: 100-107.
Online-Abstract
Lauer I, Alessandri S, Pokoj S, Reuter A, Conti A, Vieths S, Scheurer S (2008): Expression and characterization of three important panallergens from hazelnut.
Mol Nutr Food Res 52: S262-S271.
Online-Abstract
Vandenplas O, Sohy C, D'Alpaos V, Nootens C, Thimpont J, Weigand D, Scheurer S (2008): Tomato-induced occupational asthma in a greenhouse worker.
J Allergy Clin Immunol 122: 1229-1231.
Online-Abstract
Hartz C, San Miguel-Moncin MM, Cistero-Bahima A, Fötisch K, Metzner KJ, Fortunato D, Lindholm J, Vieths S, Scheurer S (2007): Molecular characterisation of Lac s 1, the major allergen from lettuce (Lactuca sativa).
Mol Immunol 44: 2820-2830.
Online-Abstract
Lauer I, San Miguel-Moncin MM, Abel T, Foetisch K, Hartz C, Fortunato D, Cistero-Bahima A, Vieths S, Scheurer S (2007): Identification of a plane pollen lipid transfer protein (Pla a 3) and its immunological relation to the peach lipid-transfer protein, Pru p 3.
Clin Exp Allergy 37: 261-269.
Online-Abstract
Crespo JF, Retzek M, Fötisch K, Sierra-Maestro E, Cid-Sanchez AB, Pascual CY, Conti A, Feliu A, Rodriguez J, Vieths S, Scheurer S (2006): Germin-like protein (Cit s 1) and profilin (Cit s 2) are major allergens in orange (Citrus sinensis) fruits.
Mol Nutr Food Res 50: 282-290.
Online-Abstract
Le LQ, Mahler V, Lorenz Y, Scheurer S, Biemelt S, Vieths S, Sonnewald U (2006): Reduced allergenicity of tomato fruits harvested from Lyc e 1-silenced transgenic tomato plants.
J Allergy Clin Immunol 118: 1176-1183.
Online-Abstract
Le Q L, Lorenz Y, Scheurer S, Fötisch K, Enrique E, Bartra J, Biemelt S, Vieths S, Sonnewald U (2006): Design of tomato fruits with reduced allergenicity by ds-RNAi mediated inhibition of ns-LTP (Lyc e 3) expression.
Plant Biotechnol J 4: 231-241.
Online-Abstract
Lorenz Y, Enrique E, LeQuynh L, Fötisch K, Retzek M, Biemelt S, Sonnewald U, Vieths S, Scheurer S (2006): Skin prick tests reveal stable and heritable reduction of allergenic potency of gene-silenced tomato fruits.
J Allergy Clin Immunol 118: 711-718.
Online-Abstract
Reuter A, Lidholm J, Andersson K, Östling J, Lundberg M, Scheurer S, Enrique E, Cistero-Bahima A, Miguel Moncin MS, Ballmer-Weber BK, Vieths S (2006): A critical assessment of allergen component-based in vitro diagnosis in cherry allergy across Europe.
Clin Exp Allergy 36: 815-823.
Online-Abstract
Rihs HP, Rueff F, Lundberg M, Rozynek P, Barber D, Scheurer S, Cistero-Bahima A, Bruning T, Raulf-Heimsoth M (2006): Relevance of the recombinant lipid transfer protein of Hevea brasiliensis: IgE-binding reactivity in fruit-allergic adults.
Ann Allergy Asthma Immunol 97: 643-649.
Online-Abstract
Scheurer S (2006): Improvement of the diagnosis of allergy by using purified allergens.
Clin Exp Allergy 36: 1483-1486.
Jahn-Schmid B, Radakovics A, Lüttkopf D, Scheurer S, Vieths S, Ebner C, Bohle B (2005): Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens.
J Allergy Clin Immunol 116: 213-219.
Online-Abstract
Reuter A, Fortunato D, Perono Garoffo L, Napolitano L, Scheurer S, Giuffrida MG, Vieths S, Conti A (2005): Novel isoforms of Pru av 1 with diverging IgE properties identified by a synergistic combination of molecular biology and proteomics.
Proteomics 5: 282-289.
Online-Abstract
Schäd SG, Trcka J, Vieths S, Scheurer S, Conti A, Bröcker EB, Trautmann A (2005): Wine anaphylaxis in a German patient: IgE-mediated allergy against a lipid transfer protein of grapes.
Int Arch Allergy Immunol 136: 159-164.
Online-Abstract
Wiche R, Gubesch M, König H, Fötisch K, Hoffmann A, Wangorsch A, Scheurer S, Vieths S (2005): Molecular basis of pollen-related food allergy: identification of a second cross-reactive IgE epitope on Pru av 1, the major cherry (Prunus avium) allergen.
Biochem J 385: 319-327.
Online-Abstract
Lauer I, Fötisch K, Kolarich D, Ballmer-Weber B, Conti A, Altmann F, Vieths S, Scheurer S (2004): Hazelnut (Corylus avellana) vicilin Cor a 11: molecular characterization of a glycoprotein and its allergenic activity.
Biochem J 383: 327-334.
Online-Abstract
Scheurer S, Lauer I, Fötisch K, Moncin MS, Retzek M, Hartz C, Enrique E, Lidholm J, Cistero-Bahima A, Vieths S (2004): Strong allergenicity of Pru av 3, the lipid transfer protein from cherry, is related to high stability against thermal processing and digestion.
J Allergy Clin Immunol 114: 900-907.
Online-Abstract
Schocker SF, Lüttkopf D, Scheurer S, Petersen A, Cistero-Bahamia A, Enrique E, San Miguel-Moncin M, Akkerdaas J, van Ree R, Vieths S, Becker WM (2004): Recombinant lipid transfer protein Cor a 8 from hazelnut: A new tool for in vitro diagnosis of potentially severe hazelnut allergy.
J Allergy Clin Immunol 113: 141-7.
Online-Abstract
Westphal S, Kempf W, Fötisch K, Retzek M, Vieths S, Scheurer S (2004): Tomato profilin Lyc e 1: IgE cross-reactivity and allergenic potency.
Allergy 59: 526-533.
Online-Abstract
Ballmer-Weber BK, Scheurer S, Vieths S (2003): Update: Kreuzreaktivität zwischen Allergenen in Nahrungsmitteln und Birkenpollen.
Allergologie 26: 463-473.
Ballmer-Weber BK, Wangorsch A, Scheurer S: Recombinant food allergens in the diagnosis of pollen-related food allergy.
In: Löwer J, Becker WM, Vieths S (Hrsg.), Regulatory Control and Standardization of Allergenic Extracts: 10th International Paul-Ehrlich-Seminar October 2-5, 2002, Lübeck. Frankfurt a. M.: Sperlich, 2003. 192-196 ISBN 3-00-012888-3
(Arbeiten aus dem Paul-Ehrlich-Institut 94)
Fötisch K, Westphal S, Lauer I, Retzek M, Altmann F, Kolarich D, Scheurer S, Vieths S (2003): Biological activity of IgE specific for cross-reactive carbohydrate determinants (CCD).
J Allergy Clin Immunol 111: 889-896.
Online-Abstract
Kaul S, Scheurer S, Danz N, Schicktanz S, Vieths S, Hoffmann A (2003): Monoclonal IgE antibodies against birch pollen allergens: novel tools for biological characterization and standardization of allergens.
J Allergy Clin Immunol 111: 1262-81.
Online-Abstract
Neudecker P, Lehmann K, Nerkamp J, Haase T, Wangorsch A, Fötisch K, Rösch P, Vieths S, Scheurer S (2003): Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure.
Biochemical J 376: 97-107.
Online-Abstract
San Miguel-Moncín M, Krail M, Scheurer S, Enrique E, Alonso R, Conti A, Cisteró-Bahíma A, Vieths S (2003): Lettuce anaphylaxis: identification of a lipid transfer protein as the major allergen.
Allergy 58: 511-7.
Online-Abstract
Westphal S, Kolarich D, Fötisch K, Lauer I, Altmann F, Conti A, Crespo JF, Rodriguez J, Enrique E, Vieths S, Scheurer S (2003): Molecular characterization and allergenic activity of Lyc e 2 (beta-fructofuranosidase), a glycosylated allergen of tomato.
Eur J Biochem 270: 1327-1337.
Online-Abstract
Ballmer-Weber BK, Scheurer S, Fritsche P, Enrique E, Cistero-Bahima A, Haase T, Wüthrich B (2002): Component-resolved diagnosis with recombinant allergens in patients with cherry allergy.
J Allergy Clin Immunol 110: 167-173.
Online-Abstract
Reindl J, Rihs HP, Scheurer S, Wangorsch A, Haustein D, Vieths S (2002): IgE reactivity to profilin in pollen-sensitized subjects with adverse reactions to banana and pineapple.
Int Arch Allergy Immunol 128: 105-114.
Online-Abstract
Vieths S, Scheurer S, Ballmer-Weber BK (2002): Current understanding of cross-reactivity of food allergens and pollen.
Ann N Y Acad Sci 964: 47-68.
Online-Abstract
Karamloo F, Scheurer S, Wangorsch A, May S, Haustein D, Vieths S (2001): Pyr c 1, the major allergen from pear, is a new member of the Bet v 1 allergen family.
J Chromatogr B Biomed Sci Appl 756: 281-293.
Online-Abstract
Kleber-Janke T, Crameri R, Scheurer S, Vieths S, Becker WM (2001): Patient-tailored cloning of allergens by phage display: Peanut (Arachis hypogaea) profilin, a food allergen derived from a rare mRNA.
J Chromatogr B Biomed Sci Appl 756: 295-305.
Online-Abstract
Lorenz AR, Scheurer S, Haustein D, Vieths S (2001): Recombinant food allergens.
J Chromatogr B Biomed Sci Appl 756: 255-279.
Online-Abstract
Neudecker P, Schweimer K, Nerkamp J, Scheurer S, Vieths S, Sticht H, Rösch P (2001): Allergic cross-reactivity made visible - the solution structure of the major cherry allergen Pru av 1.
J Biol Chem 276: 22756-22763.
Online-Abstract
Scheurer S, Pastorello EA, Wangorsch A, Kästner M, Haustein D, Vieths S (2001): Recombinant allergens Pru av 1 and Pru av 4 and a newly identified lipid transfer protein in the in vitro diagnosis of cherry allergy.
J Allergy Clin Immunol 107: 724-731.
Online-Abstract
Scheurer S, Wangorsch A, Nerkamp J, Skov PS, Ballmer-Weber BK, Wüthrich B, Haustein D, Vieths S (2001): Cross-reactivity within the profilin panallergen family investigated by comparison of recombinant profilins from pear (Pyr c 4), cherry (Pru av 4), and celery (Api g 4) with birch pollen profilin (Bet v 2).
J Chromatogr B Biomed Sci Appl 756: 315-325.
Online-Abstract
Vieths S, Scheurer S, Reindl J, Lüttkopf D, Wangosch A, Kästner M, Haase T, Haustein D (2001): Optimized allergen extracts and recombinant allergens in diagnostic applications.
Allergy 56: 78-82.
Online-Abstract
Neudecker P, Schweimer K, Nerkamp J, Boehm M, Scheurer S, Vieths S, Sticht H, Rösch P (2000): Letter to the editor: Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1.
J Biol NMR 18: 71-72.
Scheurer S, Wangorsch A, Haustein D, Vieths S (2000): Cloning of the minor allergen Api g 4, profilin from celery (Apium graveolens) and its cross-reactivity with birch pollen profilin Bet v 2.
Clin Exp Allergy 30: 962-971.
Online-Abstract
Karamloo F, Schmitz N, Scheurer S, Fötisch K, Hoffmann A, Haustein D, Vieths S (1999): Molecular cloning and characterization of a birch pollen minor allergen, Bet v 5, belonging to a family of isoflavone reductase-related proteins.
J Allergy Clin Immunol 104: 991-999.
Online-Abstract
Scheurer S, Son DY, Böhm M, Karamloo F, Franke S, Hoffmann A, Haustein D, Vieths S (1999): Cross-reactivity and epitope analysis of Pru a 1, the major cherry allergen.
Mol Immunol 36: 155-167.
Online-Abstract
Son DY, Scheurer S, Hoffmann A, Haustein D, Vieths S (1999): Pollen-related food allergy: cloning and immunological analysis of isoforms and mutants of Mal d 1, the major apple allergen, and Bet v 1, the major birch pollen allergen.
Eur J Nutr 38: 201-215.
Online-Abstract
Vieths S, Frank E, Scheurer S, Meyer HE, Hrazdina G, Haustein D (1998): Characterisation of a new IgE-binding 35-kDa protein from birch pollen with cross-reacting homologues in various plant foods.
Scand J Immunol 47: 263-272.
Online-Abstract
Hoffmann A, Vogel L, Scheurer S, Vieths S, Haustein D (1997): Potency determination of allergenic extracts using mediator release of rat basophil leukemia cells.
Arbeiten aus dem Paul-Ehrlich-Institut 91: 203-208.
Scheurer S, Metzner K, Haustein D, Vieths S (1997): Molecular cloning, expression and characterization of Pru a 1, the major cherry allergen.
Mol Immunol 34: 619-629.
Online-Abstract
