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Seasonal Influenza 2021/2022

Information on the vaccines approved in Germany, the approved vaccine doses and the vaccine base composition for the 2021/2022 season

Vaccines

The basic composition of the influenza vaccines has to be adapted to the current epidemiological situation every year because the properties of the circulating influenza viruses change. The exact composition is determined each year by the World Health Organization (WHO). This adjustment is checked for each vaccine in a procedure to change the approval. After approval of the strain adaptation, the Paul-Ehrlich-Institut tests and releases the manufactured influenza vaccines in batches, which can then be put on the market and used.

Released Vaccine Doses

Kumulative Anzahl der freigegebenen Dosen Influenza-Impfstoffe in Deutschland / Cumulative number of released doses of influenza vaccines in Germany (Stand/ as of: 28.11.2021) Stand/ as of: 28.11.2021 (Quelle / Source: Paul-Ehrlich-Institut)

DateCalendar-
week
Number of Doses of Vaccines
(total Number)
28.11.202147aprox 34.2 Million
21.11.202146aprox 33.8 Million
14.11.202145aprox 33.8 Million
07.11.202144aprox 33 Million
31.10.202143aprox 32.2 Million
24.10.202142aprox 29.8 Million
17.10.202141aprox 28.9 Million
10.10.202140aprox 25 Million
03.10.202139aprox 22.8 Million
26.09.202138aprox. 22.5 Million
19.09.202137aprox. 18.9 Million
12.09.202136aprox. 16.8 Million
05.09.202135aprox. 13 Million
29.08.202134aprox. 10.7 Million
22.08.202133aprox. 10.2 Million
15.08.202132aprox. 7.3 Million
08.08.202131aprox. 4.8 Million

Composition of Influenza virus Vaccines 2021/2022

The influenza vaccine for the 2021/2022 season is composed of the antigens of globally circulating variants of viruses according to the recommendations of the WHO and the Committee for Medicinal Products for Human Use (CHMP) at the European Medicines Agency (EMA).

This composition differs from that of the 2020/2021 season.

Strains suitable for Production in the 2021/2022 Season

Chicken egg-based Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Victoria/2570/2019 (H1N1)pdm09-like virus
  • reassortant virus IVR-215, derived from A/Victoria/2570/2019
A/Cambodia/e0826360/2020 (H3N2)-like virus
  • reassortant virus IVR-224, derived from A/Cambodia/e0826360/2019
  • reassortant virus NIB-221, derived from A/Tasmania/503/2020
B/Washington/02/2019 (B/Victoria lineage)-like virus
  • B/Washington/02/2019 (wild type)
  • reassortant virus BVR-11, derived from B/Victoria/705/2018
B/Phuket/3073/2013 - like virus (B/Yamagata lineage)
  • B/Phuket/3073/2013 (wild type)
  • reassortant virus BVR-1B, derived from B/Phuket/3073/2013

Cell-based Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Wisconsin/588/2019 (H1N1)pdm09-like virusA/Washington/19/2020 (wild type)
A/Cambodia/e0826360/2020 (H3N2)-like virusA/Tasmania/503/2020 (wild type)
B/Washington/02/2019 (B/Victoria lineage)-like virusB/Darwin/7/2019 (wild type)
B/Phuket/3073/2013 - like virus (B/Yamagata lineage)B/Singapore/INFTT-16-0610/2016 (wild type)

Live attenuated Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Victoria/2570/2019 (H1N1)pdm09-like virusVirus MEDI 340505, derived from A/Victoria/1/2020
A/Cambodia/e0826360/2020 (H3N2)-like virusVirus MEDI 339018, derived from A/Tasmania/503/2020
B/Washington/02/2019 (B/Victoria lineage)-like virusVirus MEDI 323797, derived from B/Washington/02/2019
B/Phuket/3073/2013 - like virus (B/Yamagata lineage)Virus MEDI 306444, derived from B/Phuket/3073/2013

* A and B denote the virus types, the place name refers to the place of virus isolation; the first digit indicates the number of the isolated strain, the second refers to the year of isolation. H and N are the two most important proteins in the virus envelope hemagglutinin and neuraminidase, the number behind them indicates the hemagglutinin and neuraminidase subtype.

Updated: 13.04.2022