Paul-Ehrlich-Institut

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Seasonal Influenza 2023/2024

Information on the vaccines approved in Germany, the approved vaccine doses and the vaccine base composition for the 2023/2024 season

Vaccines

The basic composition of the influenza vaccines has to be adapted to the current epidemiological situation every year because the properties of the circulating influenza viruses change. The exact composition is determined each year by the World Health Organization (WHO). This adjustment is checked for each vaccine in a procedure to change the approval. After approval of the strain adaptation, the Paul-Ehrlich-Institut tests and releases the manufactured influenza vaccines in batches, which can then be put on the market and used.

Released Vaccine Doses

Kumulative Anzahl der freigegebenen Dosen Influenza-Impfstoffe in Deutschland / Cumulative number of released doses of influenza vaccines in Germany (Stand/ as of: 26.11.2023 / 26 November 2023) Stand/ as of: 26.11.2023 / 26 November 2023 (Quelle / Source: Paul-Ehrlich-Institut)

DateCalendar-
week
Number of Doses of Vaccines
(total Number)
26 November 202347aprox. 23.1 Million
19 November 202346aprox. 22.9 Million
12 November 202345aprox. 22.9 Million
5 November 202344aprox. 22.9 Million
29 October 202343aprox. 22.2 Million
22 October 202342aprox. 21.9 Million
15 October 202341aprox. 21.8 Million
8 October 202340aprox. 21.6 Million
1 October 202339aprox. 21.3 Million
24 September 202338aprox. 20.2 Million
17 September 202337aprox. 18.8 Million
10 September 202336aprox. 15.6 Million
3 September 202335aprox. 12.5 Million
27 August 202334aprox. 8.5 Million
20 August 202333aprox. 7.7 Million
13 August 202332aprox. 6.5 Million

Composition of Influenza Virus Vaccines for the 2023/2024 Season

The influenza vaccine for the 2023/2024 season is composed of the antigens of globally circulating variants of viruses according to the recommendations of the WHO and the Committee for Medicinal Products for Human Use (CHMP) at the European Medicines Agency (EMA).

This composition differs from that of the 2022/2023 season.

Egg-based Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Victoria/4897/2022 (H1N1)pdm09-like virus
  • reassortant virus IVR-238, derived from A/Victoria/4897/2022
A/Darwin/9/2021 (H3N2)-like virus
  • reassortant virus IVR-227, derived from A/Darwin/6/2021
  • reassortant virus IVR-228, derived from A/Darwin/9/2021
  • reassortant virus SAN-010, derived from A/Darwin/9/2021
B/Austria/1359417/2021 (B/Victoria lineage)-like virus
  • B/Michigan/01/2021 (wild type)
  • reassortant virus BVR-26, derived from B/Austria/1359417/2021
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
  • B/Phuket/3073/2013 (wild type)
  • reassortant virus BVR-1B, derived from B/Phuket/3073/2013

Cell-based Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Wisconsin/67/2022 (H1N1)pdm09-like virusreassortant virus CVR-167, derived from A/Georgia/12/2022
A/Darwin/6/2021 (H3N2)-like virusA/Darwin/11/2021 (wild type)
B/Austria/1359417/2021 (B/Victoria lineage)-like virusB/Singapore/WUH4618/2021 (wild type)
B/Phuket/3073/2013 (B/Yamagata lineage)-like virusB/Singapore/INFTT-16-0610/2016 (wild type)

Live attenuated Vaccines

WHO Recommendations* for the northern hemisphereSuitable strains according to the recommendations of the EMA
A/Victoria/4897/2022 (H1N1)pdm09-like virusVirus MEDI 369815, derived from A/Norway/31694/2022
A/Darwin/9/2021 (H3N2)-like virusVirus MEDI 355293, derived from A/Norway/16606/2021
B/Austria/1359417/2021 (B/Victoria lineage)-like virusVirus MEDI 355292, derived from B/Austria/1359417/2021
B/Phuket/3073/2013 (B/Yamagata lineage)-like virusVirus MEDI 306444, derived from B/Phuket/3073/2013

* A and B denote the virus types, the place name refers to the place of virus isolation; the first digit indicates the number of the isolated strain, the second refers to the year of isolation. H and N are the two most important proteins in the virus envelope hemagglutinin and neuraminidase, the number behind them indicates the hemagglutinin and neuraminidase subtype.

Updated: 08.04.2024