Seasonal Influenza 2024/2025
Information on the vaccines approved in Germany, the approved vaccine doses and the vaccine base composition for the 2024/2025 season
Vaccines
The basic composition of the influenza vaccines has to be adapted to the current epidemiological situation every year because the properties of the circulating influenza viruses change. The exact composition is determined each year by the World Health Organization (WHO). This adjustment is checked for each vaccine in a procedure to change the approval. After approval of the strain adaptation, the Paul-Ehrlich-Institut tests and releases the manufactured influenza vaccines in batches, which can then be put on the market and used.
Released Vaccine Doses
Stand/ as of: 24.11.2024 / 24 November 2024 (Quelle / Source: Paul-Ehrlich-Institut)
Date | Calendar-
week | Number of Doses of Vaccines
(total Number) |
---|
24 November 2024 | 47 | aprox. 20.0 Million |
17 November 2024 | 46 | aprox. 19.9 Million |
10 November 2024 | 45 | aprox. 19.9 Million |
3 November 2024 | 44 | aprox. 19.9 Million |
27 October 2024 | 43 | aprox. 19.9 Million |
20 October 2024 | 42 | aprox. 19.9 Million |
13 October 2024 | 41 | aprox. 19.8 Million |
6 October 2024 | 40 | aprox. 18.7 Million |
29 September 2024 | 39 | aprox. 18.7 Million |
22 September 2024 | 38 | aprox. 18.1 Million |
15 September 2024 | 37 | aprox. 17.6 Million |
8 September 2024 | 36 | aprox. 16.9 Million |
1 September 2024 | 35 | aprox. 15.5 Million |
25 August 2024 | 34 | aprox. 14.2 Million |
18 August 2024 | 33 | aprox. 12.1 Million |
11 August 2024 | 32 | aprox. 11 Million |
4 August 2024 | 31 | aprox. 5.6 Million |
Composition of Influenza Virus Vaccines for the 2024/2025 Season
The influenza vaccine for the 2024/2025 season is composed of the antigens of globally circulating variants of viruses according to the recommendations of the WHO and the Committee for Medicinal Products for Human Use (CHMP) at the European Medicines Agency (EMA).
This composition differs from that of the 2023/2024 season.
Composition of Trivalent Vaccines
Egg-based Vaccines
WHO Recommendations* for the northern hemisphere | Suitable strains according to the recommendations of the EMA |
---|
A/Victoria/4897/2022 (H1N1)pdm09-like virus | - reassortant virus IVR-238, which is derived from A/Victoria/4897/2022
|
A/Thailand/8/2022 (H3N2)-like virus | - reassortant virus IVR-237, which is derived from A/Thailand/8/2022
- reassortant virus SAN-022, which is derived from A/California/122/2022
|
B/Austria/1359417/2021 (B/Victoria lineage)-like virus | - B/Michigan/01/2021 (wild type)
- reassortant virus BVR-26, which is derived from B/Austria/1359417/2021
|
Cell-based Vaccines
WHO Recommendations* for the northern hemisphere | Suitable strains according to the recommendations of the EMA |
---|
A/Wisconsin/67/2022 (H1N1)pdm09-like virus | - reassortant virus CVR-167, which is derived from A/Georgia/12/2022
|
A/Massachusetts/18/2022 (H3N2)-like virus | - A/California/45/2023 (wild type)
|
B/Austria/1359417/2021 (B/Victoria lineage)-like virus | - B/Singapore/WUH4618/2021 (wild type)
|
Live attenuated Vaccines
WHO Recommendations* for the northern hemisphere | Suitable strains according to the recommendations of the EMA |
---|
A/Victoria/4897/2022 (H1N1)pdm09-like virus | Virus MEDI 369815, which is derived from A/Norway/31694/2022 |
A/Thailand/8/2022 (H3N2)-like virus | Virus MEDI 370626, which is derived from A/Thailand/8/2022 |
B/Austria/1359417/2021 (B/Victoria lineage)-like virus | Virus MEDI 355292, which is derived from B/Austria/1359417/2021 |
Composition of Quadrivalent Vaccines
For the production of inactivated quadrivalent vaccines containing two influenza B virus strains, a B/Phuket/3073/2013 (B/Yamagata lineage)-like strain is considered suitable for the 2024/2025 season in addition to the strains mentioned above.
Egg-based Vaccines
WHO Recommendations* for the northern hemisphere | Suitable strains according to the recommendations of the EMA |
---|
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus | - B/Phuket/3073/2013 (wild type)
- reassortant virus BVR-1B, which is derived from B/Phuket/3073/2013
|
Cell-based Vaccines
WHO Recommendations* for the northern hemisphere | Suitable strains according to the recommendations of the EMA |
---|
B/Phuket/3073/2013 (B/Yamagata lineage)-like virus | - B/Singapore/INFTT-16-0610/2016 (wild type)
|
* A and B denote the virus types, the place name refers to the place of virus isolation; the first digit indicates the number of the isolated strain, the second refers to the year of isolation. H and N are the two most important proteins in the virus envelope hemagglutinin and neuraminidase, the number behind them indicates the hemagglutinin and neuraminidase subtype.
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