Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Gabriele Unger | Activity as WHO Collaborating Center for Blood Products an IVD Devices | 01.01.2010 - 31.12.2025 |
| Prof Dr van Ger Zandbergen | Establishment of an assessment system for innovative adjuvants | 01.07.2015 - 31.03.2020 |
| Dr Renate König | Regulatory use of BigData strategies based on OMICS data for efficient development, approval and safe use of biological medicinal products | 01.12.2021 - 31.12.2026 |
| Prof Dr Ger van Zandbergen | Regulatory research on quality data (physicochemical and functional assays) versus clinical data (PK and phase 3 efficacy study) in the approval of biosimilars | 01.10.2022 - 30.06.2025 |
| Dr Heidi Meyer | GHPP | Regulatory capacity building in the area of vaccines - Training and scientific advice for the establishment of the State Batch Tests (VaccRelease) | 01.01.2023 -31.12.2025 |
| Dr Heidi Meyer | GHPP | Regulatory capacity building in the area of vaccines - Training and advice on clinical trials and pharmacovigilance (VaccTrain 2.0) | 01.01.2023 - 31.12.2025 |
| Dr Jens Reinhardt | GHPP | Availability, quality and safety of blood and blood products in Africa (BloodTrain Next Generation) | 01.01.2023 - 31.12.2025 |
| Prof Dr Zoe Waibler | Development of methods for comparative analysis of the potency of monoclonal antibodies | 01.04.2023 - 31.03.2026 |
| PD Dr Christel Kamp | Raman spectroscopy as a digital, non-destructive method of quality control in batch testing to improve the quality of supply | 01.05.2023 - 30.04.2026 |
| Dr Dr Doris Oberle | prevCOV | Improving the prevention and treatment of long COVID and post-VAC by identifying relevant factors that influence the risk of development and progression | 15.11.2024 - 14.11.2027 |
| Dr Dr Doris Oberle | COVYOUTHdata | Recognising, understanding and coping with the long-term consequences at an early stage | 01.01.2025 - 31.12.2028 |
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Nadine Kirsch-Stefan, Dr Christoph Conrad | OSRA-PEI | 01.01.2021 - 28.02.2026 |
| Dr Michael Mühlebach | Joint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform | 01.01.2021 - 28.02.2026 |
| Dr Bevan Sawatsky | DZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions | 01.02.2021 - 28.02.2026 |
| Prof Dr Oleg Krut, Dr Ingo Spreitzer | Establishment of the monocyte activation test in the risk assessment of masked endotoxins in medicinal products (PyroSafe) | 01.04.2022 - 31.03.2025 |
| Dr Elisabeth Balks | Alternative methods: Development of an antibody-based, functional and a spectroscopic in vitro alternative for batch testing of bovine tuberculin (tuberculin) | 01.04.2023 - 31.03.2026 |
| Dr Sarah Altrichter-Dünnes | PDU_CARB-X: Product Development Unit (PDU) of the German Centre for Infection Research (DZIF) as CARB-X Accelerator | 01.10.2023 - 31.12.2026 |
| Dr Olga Tichá | Alternative methods: Characterisation of immunodominant epitopes of tetanus toxoid vaccines (TT-TOP) | 01.04.2024 - 31.03.2027 |
| Dr Michael Mühlebach | SERIMM – Serotonin and immunomodulation in ME/CFS – Development and analysis of a SARS-CoV-2-induced golden hamster animal model for ME/CFS | 01.10.2024 - 31.12.2026 |
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Renate König | Targeting converging mechanisms of inefficient immunity in tumor diseases and chronic infections | 01.01.2022 - 31.12.2025 |
| Prof Dr Eberhard Hildt | HBV over time: characteristics of viral pathogenesis in different disease phases | 01.03.2022 - 28.02.2025 |
| Dr Jessica Roos | Investigation of nitroalkylation as a novel endogenous regulatory mechanism and therapeutic target on the ubiquitin-proteasome system | 01.01.2023 - 31.12.2025 |
| Prof Dr Thorsten Jürgen Maier | Investigation on the effects of carbapenems on leukocyte-endothelial interaction in models of pulmonary inflammation and viral infection | 01.02.2023 - 31.01.2026 |
| Dr Jacomina Krijnse-Locker | Deciphering the molecular mechanism of vaccinia virus mRNA release | 01.04.2023 - 31.03.2026 |
| Prof Dr Zoltan Ivics | Targeted genome integration through genetically engineered transposon and CRISPR/Cas9 components | 01.09.2023 - 31.08.2026 |
| Prof Dr Ger van Zandbergen | Molecular and cellular characterisation of the importance of cell death processes for host cell exit and cell-to-cell transfer of Leishmania | 15.04.2024 - 14.04.2027 |
| Prof Dr Christian Buchholz | Identification and overcoming of therapy barriers for CAR-T cells in the microenvironment of colorectal carcinoma | 01.11.2024 - 31.10.2027 |
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Zoe Waibler | imSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology | 01.11.2019 - 31.10.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | COMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections | 01.11.2019 - 31.10.2025 |
| Prof Dr Zoltan Ivics Prof Dr Christian Buchholz | T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy | 01.01.2021 - 31.12.2025 |
| Dr J. Hartmann | T-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer | 01.03.2021 - 28.02.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | INNO4VAC | Innovations to accelerate vaccine development and manufacture | 01.09.2021 - 28.02.2027 |
| Prof Dr Thomas Holzhauser | ALLPreT | Allergenicity Prediction Toolbox for novel foods | 01.09.2022 - 31.08.2026 |
| Prof Dr Isabelle Bekeredjian-Ding Dr Maximilian Ehrhardt | CHESSMEN | Coordination and Harmonization of the Existing Systems against Shortage of Medicine – European Network | 16.01.2023 - 15.01.2025 |
| Bettina Ziegele | IncreaseNET | Supporting the increased capacity and competence building of the EU medicines regulatory network | 01.01.2024 - 31.12.2026 |
| Prof Dr Karin Metzner | EURL-IVD.1 | Harmonization process of European Reference Laboratories for in vitro diagnosis | 01.02.2024 - 31.01.2025 |
| Prof Dr Christian Buchholz | ERDERA | European Rare Diseases Research Alliance | 01.09.2024 - 31.08.2031 |
| Dr Renate König | VIROMARKERS | Virus related biomarkers to improve management of chronic conditions | 01.02.2025 - 31.01.2028 |
| Dr Dirk Mentzer | Medicines regulatory systems strengthening in Sub-Saharan Africa | 01.01.2025 - 31.12.2025 |
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | Vektor-Core | 01.01.2023 - 31.12.2025 |
| Prof Dr Christian Buchholz | LOEWE CARISMa | Optimisation of CAR cell therapies by influencing the immunosuppressive tumour microenvironment | 01.01.2025 - 31.12.2028 |
DAAD | German Academic Exchange Service
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Stephan Scheurer | Anti-allergic effect of apple derived pectin: A novel immunomodulatory function | 01.01.2024-31.12.2025 |
EDQM | European Directorate for the Quality of Medicine
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths | Recombinant major allergens (BRPs and assay methods) | undetermined |
ISBT | International Society of Blood Transfusion
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Marcel Prax | Establishment of platelet bacterial reference strains in BioBall format | from 2019 |
Rudolf Marx Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Ger van Zandbergen Prof Dr Jacomine Krijnse Locker | Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell culture | indefinite |
Phospholipid Research Center
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | Receptor-targeted lipid nanoparticles for mRNA delivery into T lymphocytes | 01.03.24 - 28.02.26 |
FIMABIS | Fundacion Para La Investigacion De Malaga Enbiomedicina Y Salud
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Stephan Scheurer | Analysis of the clinical efficacy and immunomodulatory effect of pectin in LTP allergic patients through a placebocontrolled intervention study and long-term follow-up | 01.01.2024 - 31.12.2026 |
SNF | Swiss National Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Renate König | Molecular Mechanisms of Human Interferon System Deficiency | 01.04.2025 - 31.03.2029 |
Wilhelm Sander Stiftung
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Eberhard Hildt | Characterisation of a HBsAg/HDAg nanoparticle as a therapeutic and prophylactic vaccine against hepatitis B and D co-infection | 01.11.2024 - 31.10.2026 |
Updated: 13.02.2025
